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Dokumenttyp:
journal article 
Autor(en):
Kremer, P; Mahmoudreza, F; Ding, R; Pritsch, M; Zoubaa, S; Frei, E 
Titel:
Intraoperative fluorescence staining of malignant brain tumors using 5-aminofluorescein-labeled albumin. 
Abstract:
OBJECTIVE: The newly developed conjugate 5-aminofluorescein (AFL)-human serum albumin (HSA) was investigated in a clinical trial for fluorescence-guided surgery of malignant brain tumors to assess its efficacy and tolerability. METHODS: AFL, covalently linked to human serum albumin at a molar ratio of 1:1, was administered intravenously 0.5 to 4 days before surgery at 0.5 or 1.0 mg/kg of body weight to 13 patients aged 38 to 71 years who were suspected of having malignant gliomas. Fluorescence g...    »
 
Zeitschriftentitel:
Neurosurgery 
Jahr:
2009 
Band / Volume:
64 
Heft / Issue:
3 Suppl 
Seitenangaben Beitrag:
53-60; discussion 60-1 
Sprache:
eng 
Print-ISSN:
0148-396X 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie