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Dokumenttyp:
journal article 
Autor(en):
Drzezga, A; Grimmer, T; Henriksen, G; Mühlau, M; Perneczky, R; Miederer, I; Praus, C; Sorg, C; Wohlschläger, A; Riemenschneider, M; Wester, HJ; Foerstl, H; Schwaiger, M; Kurz, A 
Titel:
Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. 
Abstract:
OBJECTIVE: To examine the influence of the APOE genotype on levels of beta-amyloid (Abeta) plaque load and atrophy in patients with Alzheimer disease (AD) in vivo. METHODS: Thirty-two patients with moderate AD were divided into carriers and noncarriers of the epsilon4 allele. These groups were matched for age, disease duration, education, and cognitive impairment. In all subjects, [11C]PIB-PET was performed for measurement of cerebral Abeta plaque deposition and cranial MRI for the assessment of...    »
 
Zeitschriftentitel:
Neurology 
Jahr:
2009 
Band / Volume:
72 
Heft / Issue:
17 
Seitenangaben Beitrag:
1487-94 
Sprache:
eng 
Print-ISSN:
0028-3878 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik; r Psychiatrie und Psychotherapie; Neurologische Klinik und Poliklinik; r Neuroradiologie