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Dokumenttyp:
journal article 
Autor(en):
Walter, M; Philotheou, A; Bonnici, F; Ziegler, AG; Jimenez, R; NBI-6024 Study Group 
Titel:
No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes. 
Abstract:
OBJECTIVE: This randomized, four-arm, placebo-controlled, dose-ranging phase 2 trial was conducted to determine whether repeated subcutaneous injections of the altered peptide ligand, NBI-6024, designed to inhibit autoreactive T-cells, improves beta-cell function in patients with recently diagnosed type 1 diabetes. RESEARCH DESIGN AND METHODS: A total of 188 patients, aged 10-35 years, with recently diagnosed type 1 diabetes were randomly assigned for a treatment consisting of the subcutaneous a...    »
 
Zeitschriftentitel:
Diabetes Care 
Jahr:
2009 
Band / Volume:
32 
Heft / Issue:
11 
Seitenangaben Beitrag:
2036-40 
Sprache:
eng 
Print-ISSN:
0149-5992 
TUM Einrichtung:
Kinderklinik und Poliklinik