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Dokumenttyp:
journal article 
Autor(en):
Decker, T; Sandherr, M; Goetze, K; Oelsner, M; Ringshausen, I; Peschel, C 
Titel:
A pilot trial of the mTOR (mammalian target of rapamycin) inhibitor RAD001 in patients with advanced B-CLL. 
Abstract:
Although B-cell chronic lymphocytic leukemia (CLL) is treatable, it remains an incurable disease and most patients inevitably suffer relapse. Many therapeutic options exist for those requiring therapy, including monoclonal antibodies and stem cell transplantation, but remissions tend to last shorter in the course of the disease. Targeting the cell cycle has recently been realized to be an attractive therapeutic approach in solid and hematological malignancies, and the proliferative nature of B-C...    »
 
Zeitschriftentitel:
Ann Hematol 
Jahr:
2009 
Band / Volume:
88 
Heft / Issue:
Seitenangaben Beitrag:
221-7 
Sprache:
eng 
Print-ISSN:
0939-5555 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik