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Dokumenttyp:
journal article 
Autor(en):
Schilling, G; Bruweleit, M; Harbeck, N; Thomssen, C; Becker, K; Hoffmann, R; Villena, C; Schütte, M; Hossfeld, DK; Bokemeyer, C; de Wit, M 
Titel:
Phase II trial of vinorelbine and trastuzumab in patients with HER2-positive metastatic breast cancer. A prospective, open label, non-controlled, multicenter phase II trial (to investigate efficacy and safety of this combination chemotherapy). 
Abstract:
The purpose of this study was to evaluate the efficacy (progression free survival (PFS) and response rate) and safety of vinorelbine and trastuzumab combination chemotherapy in patients with HER2-overexpressing, metastatic breast cancer as a first line chemotherapy regimen. Patients with histologically confirmed, HER2-positive (immunohistochemistry (ICH) 3+, or 2+ and FISH+) metastatic breast cancer who had nor received prior vinorelbine or anti-HER2 therapy in the adjuvant setting, received at...    »
 
Zeitschriftentitel:
Invest New Drugs 
Jahr:
2009 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
166-72 
Sprache:
eng 
Print-ISSN:
0167-6997 
TUM Einrichtung:
Frauenklinik und Poliklinik