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Document type:
journal article 
Author(s):
Bessler, WG; Puce, K; vor dem Esche, U; Kirschning, C; Huber, M 
Title:
Immunomodulating effects of OM-89, a bacterial extract from Escherichia coli, in murine and human leukocytes. 
Abstract:
OM-89 (Uro-Vaxom) is a bacterial extract prepared from 18 uropathogenic Escherichia coli strains used for the prevention and treatment of recurrent infections of the urinary tract. The immunomodulating effects of the bacterial extract were investigated in a mouse model. After a single oral administration of OM-89, leukocyte activation was demonstrated ex vivo in blood and liver cells using a chemiluminescence assay. An increase of the production of tumor necrosis factor-alpha (TNF-alpha) in supe...    »
 
Journal title abbreviation:
Arzneimittelforschung 
Year:
2009 
Journal volume:
59 
Journal issue:
11 
Pages contribution:
571-7 
Language:
eng 
Print-ISSN:
0004-4172 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene