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Document type:
journal article 
Author(s):
Siegemund, S; Hartl, A; von Buttlar, H; Dautel, F; Raue, R; Freudenberg, MA; Fejer, G; Büttner, M; Köhler, G; Kirschning, CJ; Sparwasser, T; Alber, G 
Title:
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis. 
Abstract:
Parapoxvirus ovis (PPVO) is a member of the Poxviridae family and belongs to the genus Parapoxvirus. It displays only limited homology with orthopoxviruses and has some molecular features such as an unusual high GC content distinct from orthopoxviruses. Inactivated PPVO (iPPVO) displays strong immunostimulatory capacities mediating antiviral activity in vivo. The role of dendritic cells (DC) and the pattern recognition receptors and signaling requirements responsible for immunostimulation by iPP...    »
 
Journal title abbreviation:
J Virol 
Year:
2009 
Journal volume:
83 
Journal issue:
18 
Pages contribution:
9411-22 
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene