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Document type:
journal article 
Author(s):
Frenzel, LP; Abdullah, Z; Kriegeskorte, AK; Dieterich, R; Lange, N; Busch, DH; Krönke, M; Utermöhlen, O; Hescheler, J; Sari?, T 
Title:
Role of natural-killer group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes. 
Abstract:
The transplantation of cardiomyocytes derived from embryonic stem (ES) cells into infarcted heart has been shown to improve heart function in animal models. However, immune rejection of transplanted cells may hamper the clinical application of this approach. Natural killer (NK) cells could play an important role in this process in both autologous and allogeneic settings by eliminating cells expressing low levels of major histocompatibility complex (MHC) class I molecules. Here we characterize em...    »
 
Journal title abbreviation:
Stem Cells 
Year:
2009 
Journal volume:
27 
Journal issue:
Pages contribution:
307-16 
Language:
eng 
Print-ISSN:
1066-5099 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene