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Document type:
journal article 
Author(s):
Higuchi, T; Anton, M; Dumler, K; Seidl, S; Pelisek, J; Saraste, A; Welling, A; Hofmann, F; Oostendorp, RA; Gansbacher, B; Nekolla, SG; Bengel, FM; Botnar, RM; Schwaiger, M 
Title:
Combined reporter gene PET and iron oxide MRI for monitoring survival and localization of transplanted cells in the rat heart. 
Abstract:
There is a need for in vivo monitoring of cell engraftment and survival after cardiac cell transplantation therapy. This study assessed the feasibility and usefulness of combined PET and MRI for monitoring cell engraftment and survival after cell transplantation. METHODS: Human endothelial progenitor cells (HEPCs), derived from CD34+ mononuclear cells of umbilical cord blood, were retrovirally transduced with the sodium iodide symporter (NIS) gene for reporter gene imaging by (124)I-PET and labe...    »
 
Journal title abbreviation:
J Nucl Med 
Year:
2009 
Journal volume:
50 
Journal issue:
Pages contribution:
1088-94 
Language:
eng 
Print-ISSN:
0161-5505 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik; r experimentelle Onkologie und Therapieforschung; r Allgemeine Pathologie und pathologische Anatomie; chirurgie; r Pharmakologie und Toxikologie; III. Medizinische Klinik und Poliklinik