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Document type:
Zeitschriftenaufsatz 
Author(s):
Paul, V.; Meyer, H.H.D.; Leidl, K.; Soumian, S.; Albrecht, C 
Title:
A novel enzyme immunoassay specific for ABCA 1 protein quantification in human tissues and cells 
Abstract:
ATP-binding cassette transporter A1 (ABCA1) mediates the transport of cholesterol and phospholipids from cells to lipid-poor HDL and maintains cellular lipid homeostasis. Impaired ABCA1 function plays a role in lipid disorders, cardiovascular disease, atherosclerosis, and metabolic disorders. Despite the clinical importance of ABCA1, no method is available for quantifying ABCA1 protein. We developed a sensitive indirect competitive ELISA for measuring ABCA1 protein in human tissues using a...    »
 
Keywords:
ATP binding cassette transporter A1 • ELISA • carotid plaques 
Journal title:
Journal of Lipid Research 
Year:
2008 
Journal volume:
49 
Pages contribution:
2259-2267 
Language:
en 
WWW:
TUM Institution:
Zentralinstitut für Ernährungs- und Lebensmittelforschung / Abteilung Physiologie 
Format:
Text