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Document type:
journal article 
Author(s):
Wang-Sattler, R; Yu, Y; Mittelstrass, K; Lattka, E; Altmaier, E; Gieger, C; Ladwig, KH; Dahmen, N; Weinberger, KM; Hao, P; Liu, L; Li, Y; Wichmann, HE; Adamski, J; Suhre, K; Illig, T 
Title:
Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study. 
Abstract:
Exposure to nicotine during smoking causes a multitude of metabolic changes that are poorly understood. We quantified and analyzed 198 metabolites in 283 serum samples from the human cohort KORA (Cooperative Health Research in the Region of Augsburg). Multivariate analysis of metabolic profiles revealed that the group of smokers could be clearly differentiated from the groups of former smokers and non-smokers. Moreover, 23 lipid metabolites were identified as nicotine-dependent biomarkers. The l...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2008 
Journal volume:
Journal issue:
12 
Pages contribution:
e3863 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie