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Dokumenttyp:
journal article 
Autor(en):
Wang-Sattler, R; Yu, Y; Mittelstrass, K; Lattka, E; Altmaier, E; Gieger, C; Ladwig, KH; Dahmen, N; Weinberger, KM; Hao, P; Liu, L; Li, Y; Wichmann, HE; Adamski, J; Suhre, K; Illig, T 
Titel:
Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study. 
Abstract:
Exposure to nicotine during smoking causes a multitude of metabolic changes that are poorly understood. We quantified and analyzed 198 metabolites in 283 serum samples from the human cohort KORA (Cooperative Health Research in the Region of Augsburg). Multivariate analysis of metabolic profiles revealed that the group of smokers could be clearly differentiated from the groups of former smokers and non-smokers. Moreover, 23 lipid metabolites were identified as nicotine-dependent biomarkers. The l...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2008 
Band / Volume:
Heft / Issue:
12 
Seitenangaben Beitrag:
e3863 
Sprache:
eng 
TUM Einrichtung:
r Psychosomatische Medizin und Psychotherapie