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Dokumenttyp:
journal article 
Autor(en):
Buttmann, M; Nowak, E; Kroner, A; Hemmer, B; Lesch, KP; Rieckmann, P 
Titel:
Analysis of the stathmin rs182455 single nucleotide promoter polymorphism in patients with multiple sclerosis. 
Abstract:
Stathmin, a steroid-responsive regulatory protein of oligodendrocyte migration and survival, is highly expressed in active brain lesions of patients with multiple sclerosis (MS) and probably involved in myelin degeneration and repair. Here, we analyzed a single nucleotide polymorphism (rs182455) within the stathmin promoter that is close to a putative steroid-responsive element and has a high minor allelic frequency, in 647 clinically well characterized MS patients and 519 healthy controls. Alle...    »
 
Zeitschriftentitel:
J Neurogenet 
Jahr:
2008 
Band / Volume:
22 
Heft / Issue:
Seitenangaben Beitrag:
181-6 
Sprache:
eng 
Print-ISSN:
0167-7063 
TUM Einrichtung:
Neurologische Klinik und Poliklinik