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Dokumenttyp:
journal article 
Autor(en):
Eyer, F; Jung, N; Neuberger, H; Witte, A; Poethko, T; Henke, J; Zilker, T 
Titel:
Seromucosal transport of intravenously administered carbamazepine is not enhanced by oral doses of activated charcoal in rats. 
Abstract:
The fate of carbamazepine after intravenous injection in rats (n = 24) and the influence of activated charcoal on the kinetics was investigated. After randomization to four groups (n = 6, each), plasma concentration and the quantities of carbamazepine and metabolites excreted into bile, urine and intestine were determined using an in situ perfusion model of the small intestine (Ringer's solution) with or without orally administered activated charcoal (AC+; AC-) and with or without bile duct can...    »
 
Zeitschriftentitel:
Basic Clin Pharmacol Toxicol 
Jahr:
2008 
Band / Volume:
102 
Heft / Issue:
Seitenangaben Beitrag:
337-46 
Sprache:
eng 
Print-ISSN:
1742-7835 
TUM Einrichtung:
Toxikologische Abteilung