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Document type:
journal article 
Author(s):
Eyer, F; Jung, N; Neuberger, H; Witte, A; Poethko, T; Henke, J; Zilker, T 
Title:
Seromucosal transport of intravenously administered carbamazepine is not enhanced by oral doses of activated charcoal in rats. 
Abstract:
The fate of carbamazepine after intravenous injection in rats (n = 24) and the influence of activated charcoal on the kinetics was investigated. After randomization to four groups (n = 6, each), plasma concentration and the quantities of carbamazepine and metabolites excreted into bile, urine and intestine were determined using an in situ perfusion model of the small intestine (Ringer's solution) with or without orally administered activated charcoal (AC+; AC-) and with or without bile duct can...    »
 
Journal title abbreviation:
Basic Clin Pharmacol Toxicol 
Year:
2008 
Journal volume:
102 
Journal issue:
Pages contribution:
337-46 
Language:
eng 
Print-ISSN:
1742-7835 
TUM Institution:
Toxikologische Abteilung