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Document type:
journal article 
Author(s):
Szebeni, B; Veres, G; Dezsõfi, A; Rusai, K; Vannay, A; Mraz, M; Majorova, E; Arató, A 
Title:
Increased expression of Toll-like receptor (TLR) 2 and TLR4 in the colonic mucosa of children with inflammatory bowel disease. 
Abstract:
Inflammatory bowel disease (IBD) may result from exaggerated stimulation of the mucosal immune system by luminal bacterial flora. Bacterial products are recognized by pattern recognition receptors such as Toll-like receptors (TLRs), which are key regulators of the innate immune system. Therefore, the expression of TLR2, TLR3 and TLR4 in colonic biopsy samples taken from children with active IBD were studied and compared to controls. Colonic biopsy samples were collected from macroscopically infl...    »
 
Journal title abbreviation:
Clin Exp Immunol 
Year:
2008 
Journal volume:
151 
Journal issue:
Pages contribution:
34-41 
Language:
eng 
Print-ISSN:
0009-9104 
TUM Institution:
r Nephrologie