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Document type:
journal article 
Author(s):
Schulz, C; Konrad, I; Sauer, S; Orschiedt, L; Koellnberger, M; Lorenz, R; Walter, U; Massberg, S 
Title:
Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo. 
Abstract:
Acetylsalicylic acid (ASA) and the thienopyridine clopidogrel are established anti-platelet drugs that significantly reduce secondary cardiovascular events in patients with manifest atherosclerosis. However, their impact on atherosclerotic lesion development remains controversial. Four-week-old ApoE-deficient mice were randomly assigned to four groups receiving a cholesterol diet together with either ASA (5 mg/kg), or clopidogrel (25 mg/kg), or a combination of both ASA and clopidogrel, or vehic...    »
 
Journal title abbreviation:
Thromb Haemost 
Year:
2008 
Journal volume:
99 
Journal issue:
Pages contribution:
190-5 
Language:
eng 
Print-ISSN:
0340-6245 
TUM Institution:
I. Medizinische Klinik und Poliklinik