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Dokumenttyp:
journal article 
Autor(en):
Hultsch, C; Blank, O; Wester, HJ; Heinrich, MR 
Titel:
Radical fluoroarylation in radiochemical synthesis 
Abstract:
In this study, we report on the radical [F-18]fluoroarylation of different olefins using 4-[F-18]fluorobenzenediazonium ions to provide a new route to radiopharmaceuticals containing a deactivated, 4-[F-18]fluoro substituted phenyl group. This new methodology was shown to be well suited for the synthesis of F-18-labelled stilbenes. Stilbene 7 is now accessible within 80 min in 30-45% overall radiochemical yield starting from [F-18]fluoride. (C) 2008 Elsevier Ltd. All rights reserved. 
Zeitschriftentitel:
Tetrahedron Lett 
Jahr:
2008 
Band / Volume:
49 
Heft / Issue:
11 
Seitenangaben Beitrag:
1881-1883 
Sprache:
eng 
Print-ISSN:
0040-4039 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik