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Dokumenttyp:
journal article 
Autor(en):
Heger, U; Weitz, J; Lordick, F 
Titel:
[Indications for pre- and postoperative treatment with imatinib for gastrointestinal stromal tumors] 
Abstract:
Imatinib is a tyrosine kinase inhibitor directed against the KIT and the PDGF-alpha receptors. Imatinib has proven efficacy in the treatment of metastatic GIST with a response rate achieving 70%, but treatment with imatinib alone is not curative. The median progression-free survival is about 2 years. In locally advanced GIST, primary treatment with imatinib proved to be safe and feasible in several cohort studies. The goal of any curatively intended surgical treatment for GIST is R0 resection. T...    »
 
Zeitschriftentitel:
Chirurg 
Jahr:
2008 
Band / Volume:
79 
Heft / Issue:
Seitenangaben Beitrag:
630-7 
Sprache:
de 
Print-ISSN:
0009-4722 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik