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Document type:
journal article 
Author(s):
Bevan, S; Dichgans, M; Wiechmann, HE; Gschwendtner, A; Meitinger, T; Markus, HS 
Title:
Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations. 
Abstract:
BACKGROUND AND PURPOSE: The recent finding that genetic variants in 5-lipoxygenase activating protein and leukotriene A4 hydrolase may confer an increased risk of ischemic stroke has implicated the leukotriene family as potential mediators of cardiovascular disease. Using a case control replication methodology, all members of the leukotriene synthesis pathway and their receptors were examined for genetic variants, which may act as risk factors for all ischemic stroke and stroke subtypes. METHODS...    »
 
Journal title abbreviation:
Stroke 
Year:
2008 
Journal volume:
39 
Journal issue:
Pages contribution:
1109-14 
Language:
eng 
Print-ISSN:
0039-2499 
TUM Institution:
r Humangenetik