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Dokumenttyp:
journal article 
Autor(en):
Schnell, O; Krebs, B; Wagner, E; Romagna, A; Beer, AJ; Grau, SJ; Thon, N; Goetz, C; Kretzschmar, HA; Tonn, JC; Goldbrunner, RH 
Titel:
Expression of integrin alphavbeta3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature. 
Abstract:
In malignant gliomas, the integrin adhesion receptors seem to play a key role for invasive growth and angiogenesis. However, there is still a controversy about the expression and the distribution of alpha(v)beta(3) integrin caused by malignancy. The aim of our study was to assess the extent and pattern of alpha(v)beta(3) integrin expression within primary glioblastomas (GBMs) compared with low-grade gliomas (LGGs). Tumor samples were immunostained for the detection of alpha(v)beta(3) integrin an...    »
 
Zeitschriftentitel:
Brain Pathol 
Jahr:
2008 
Band / Volume:
18 
Heft / Issue:
Seitenangaben Beitrag:
378-86 
Sprache:
eng 
Print-ISSN:
1015-6305 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik