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Dokumenttyp:
journal article 
Autor(en):
Willhauck, MJ; Sharif-Samani, B; Senekowitsch-Schmidtke, R; Wunderlich, N; Göke, B; Morris, JC; Spitzweg, C 
Titel:
Functional sodium iodide symporter expression in breast cancer xenografts in vivo after systemic treatment with retinoic acid and dexamethasone. 
Abstract:
CONTEXT: The sodium iodide symporter (NIS) mediates iodide uptake in the thyroid gland as well as in lactating breast, and is also expressed in the majority of breast cancers. Recently, we have reported stimulation of all-trans retinoic acid (atRA)-induced NIS expression in the human breast cancer cell line MCF-7 by dexamethasone (Dex), resulting in an enhanced therapeutic effect of (131)I in vitro. OBJECTIVE: In the current study we examined the efficacy of Dex stimulation of atRA-induced NIS e...    »
 
Zeitschriftentitel:
Breast Cancer Res Treat 
Jahr:
2008 
Band / Volume:
109 
Heft / Issue:
Seitenangaben Beitrag:
263-72 
Sprache:
eng 
Print-ISSN:
0167-6806 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik