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Document type:
journal article 
Author(s):
Holzapfel, K; Müller, SA; Seidl, C; Grosu, AL; Schwaiger, M; Senekowitsch-Schmidtke, R 
Title:
Effects of irradiation on the [Methyl-3H]choline uptake in the human prostate cancer cell lines LNCaP and PC3. 
Abstract:
BACKGROUND AND PURPOSE: Choline positron emission tomography (PET) can help to optimize radiation treatment strategy of prostate cancer. Therefore, the aim of this study was to elucidate the effects of ionizing radiation on the choline uptake in an androgen-dependent (LNCaP) and an androgen-independent (PC3) prostate cancer cell line. MATERIAL AND METHODS: Uptake of [methyl-(3)H]choline chloride was investigated between 4 and 96 h after irradiation with 6 Gy. Dose dependence of choline uptake wa...    »
 
Journal title abbreviation:
Strahlenther Onkol 
Year:
2008 
Journal volume:
184 
Journal issue:
Pages contribution:
319-24 
Language:
eng 
Print-ISSN:
0179-7158 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik