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Document type:
journal article 
Author(s):
Beer, AJ; Schwaiger, M 
Title:
Imaging of integrin alphavbeta3 expression. 
Abstract:
The integrin alphavbeta3 plays an important role in angiogenesis and tumor metastasis. It is expressed on activated endothelial cells as well as some tumor cells. Therefore it is a promising imaging target as a potential surrogate parameter of angiogenic activity. Molecular imaging of alphavbeta3 expression could potentially facilitate response evaluation of antiangiogenic drugs (e. g. bevacizumab) or aid in selecting and monitoring patients receiving humanized monoclonal antibody therapies dire...    »
 
Journal title abbreviation:
Cancer Metastasis Rev 
Year:
2008 
Journal volume:
27 
Journal issue:
Pages contribution:
631-44 
Language:
eng 
Print-ISSN:
0167-7659 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik