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Dokumenttyp:
journal article 
Autor(en):
Lange, M; Kaynak, B; Forster, UB; Tönjes, M; Fischer, JJ; Grimm, C; Schlesinger, J; Just, S; Dunkel, I; Krueger, T; Mebus, S; Lehrach, H; Lurz, R; Gobom, J; Rottbauer, W; Abdelilah-Seyfried, S; Sperling, S 
Titel:
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. 
Abstract:
Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone-DNA interactions. We present DPF3, a new epigenetic key factor for heart and muscle development characterized by a double PHD finger. DPF3 is associated with the BAF chromatin remodeling complex and binds methylated and acetylated lysine residues of histone 3 and 4. Thus, DPF3 may represent the first plant homeodomains that bind acetylated lys...    »
 
Zeitschriftentitel:
Genes Dev 
Jahr:
2008 
Band / Volume:
22 
Heft / Issue:
17 
Seitenangaben Beitrag:
2370-84 
Sprache:
eng 
Print-ISSN:
0890-9369 
TUM Einrichtung:
r Kinderkardiologie und angeborene Herzfehler