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Document type:
journal article 
Author(s):
Hammer, S; Toenjes, M; Lange, M; Fischer, JJ; Dunkel, I; Mebus, S; Grimm, CH; Hetzer, R; Berger, F; Sperling, S 
Title:
Characterization of TBX20 in human hearts and its regulation by TFAP2. 
Abstract:
The T-box family of transcription factors has been shown to have major impact on human development and disease. In animal studies Tbx20 is essential for the development of the atrioventricular channel, the outflow tract and valves, suggesting its potential causative role for the development of Tetralogy of Fallot (TOF) in humans. In the presented study, we analyzed TBX20 in cardiac biopsies derived from patients with TOF, ventricular septal defects (VSDs) and normal hearts. Mutation analysis did...    »
 
Journal title abbreviation:
J Cell Biochem 
Year:
2008 
Journal volume:
104 
Journal issue:
Pages contribution:
1022-33 
Language:
eng 
Print-ISSN:
0730-2312 
TUM Institution:
r Kinderkardiologie und angeborene Herzfehler