Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Krainick-Strobel, UE; Lichtenegger, W; Wallwiener, D; Tulusan, AH; Jänicke, F; Bastert, G; Kiesel, L; Wackwitz, B; Paepke, S 
Titel:
Neoadjuvant letrozole in postmenopausal estrogen and/or progesterone receptor positive breast cancer: a phase IIb/III trial to investigate optimal duration of preoperative endocrine therapy. 
Abstract:
BACKGROUND: In recent years, preoperative volume reduction of locally advanced breast cancers, resulting in higher rates of breast-conserving surgery (BCS), has become increasingly important also in postmenopausal women. Clinical interest has come to center on the third-generation nonsteroidal aromatase inhibitors (AIs), including letrozole, for such neoadjuvant endocrine treatment. This usually lasts 3-4 months and has been extended to up to 12 months, but optimal treatment duration has not bee...    »
 
Zeitschriftentitel:
BMC Cancer 
Jahr:
2008 
Band / Volume:
Seitenangaben Beitrag:
62 
Sprache:
eng 
TUM Einrichtung:
Frauenklinik und Poliklinik