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Document type:
journal article 
Author(s):
Krainick-Strobel, UE; Lichtenegger, W; Wallwiener, D; Tulusan, AH; Jänicke, F; Bastert, G; Kiesel, L; Wackwitz, B; Paepke, S 
Title:
Neoadjuvant letrozole in postmenopausal estrogen and/or progesterone receptor positive breast cancer: a phase IIb/III trial to investigate optimal duration of preoperative endocrine therapy. 
Abstract:
BACKGROUND: In recent years, preoperative volume reduction of locally advanced breast cancers, resulting in higher rates of breast-conserving surgery (BCS), has become increasingly important also in postmenopausal women. Clinical interest has come to center on the third-generation nonsteroidal aromatase inhibitors (AIs), including letrozole, for such neoadjuvant endocrine treatment. This usually lasts 3-4 months and has been extended to up to 12 months, but optimal treatment duration has not bee...    »
 
Journal title abbreviation:
BMC Cancer 
Year:
2008 
Journal volume:
Pages contribution:
62 
Language:
eng 
TUM Institution:
Frauenklinik und Poliklinik