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Document type:
journal article 
Author(s):
Debela, M; Beaufort, N; Magdolen, V; Schechter, NM; Craik, CS; Schmitt, M; Bode, W; Goettig, P 
Title:
Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7. 
Abstract:
Human kallikrein-related peptidases (KLKs) are (chymo)-trypsin-like serine proteinases that are expressed in a variety of tissues such as prostate, ovary, breast, testis, brain, and skin. Although their physiological functions have been only partly elucidated, many of the KLKs appear to be useful prognostic cancer markers, showing distinct correlations between their expression levels and different stages of cancer. Recent advances in the purification of'new type' recombinant KLKs allowed solutio...    »
 
Journal title abbreviation:
Biol Chem 
Year:
2008 
Journal volume:
389 
Journal issue:
Pages contribution:
623-32 
Language:
eng 
Print-ISSN:
1431-6730 
TUM Institution:
Frauenklinik und Poliklinik