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Dokumenttyp:
journal article 
Autor(en):
Hennig, R; Osman, T; Esposito, I; Giese, N; Rao, SM; Ding, XZ; Tong, WG; Büchler, MW; Yokomizo, T; Friess, H; Adrian, TE 
Titel:
BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation. 
Abstract:
Pancreatic cancer has an abysmal prognosis. Targets for early detection, prevention and therapy are desperately needed. Inflammatory pathways have an important impact on tumour growth and progression. Expression of BLT2 (the second leukotriene B(4) receptor) was investigated by real-time RT-PCR and immunohistochemistry. Cell proliferation was studied after stable transfection with BLT2, after treatment with siRNA and Compound A as an agonist. BLT2 is expressed in all pancreatic cancer cell lines...    »
 
Zeitschriftentitel:
Br J Cancer 
Jahr:
2008 
Band / Volume:
99 
Heft / Issue:
Seitenangaben Beitrag:
1064-73 
Sprache:
eng 
Print-ISSN:
0007-0920 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik