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Document type:
journal article 
Author(s):
Hennig, R; Osman, T; Esposito, I; Giese, N; Rao, SM; Ding, XZ; Tong, WG; Büchler, MW; Yokomizo, T; Friess, H; Adrian, TE 
Title:
BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation. 
Abstract:
Pancreatic cancer has an abysmal prognosis. Targets for early detection, prevention and therapy are desperately needed. Inflammatory pathways have an important impact on tumour growth and progression. Expression of BLT2 (the second leukotriene B(4) receptor) was investigated by real-time RT-PCR and immunohistochemistry. Cell proliferation was studied after stable transfection with BLT2, after treatment with siRNA and Compound A as an agonist. BLT2 is expressed in all pancreatic cancer cell lines...    »
 
Journal title abbreviation:
Br J Cancer 
Year:
2008 
Journal volume:
99 
Journal issue:
Pages contribution:
1064-73 
Language:
eng 
Print-ISSN:
0007-0920 
TUM Institution:
Chirurgiesche Klinik und Poliklinik