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Document type:
journal article 
Author(s):
Keates, AC; Tummala, S; Peek, RM; Csizmadia, E; Kunzli, B; Becker, K; Correa, P; Romero-Gallo, J; Piazuelo, MB; Sheth, S; Kelly, CP; Robson, SC; Keates, S 
Title:
Helicobacter pylori infection stimulates plasminogen activator inhibitor 1 production by gastric epithelial cells. 
Abstract:
Chronic infection with the gastric pathogen Helicobacter pylori significantly increases the risk of developing atrophic gastritis, peptic ulcer disease, and gastric adenocarcinoma. H. pylori strains that possess the cag pathogenicity island, which translocates CagA into the host cells, augment these risks. The aim of this study was to determine the molecular mechanisms through which H. pylori upregulates the expression of plasminogen activator inhibitor 1 (PAI-1), a member of the urokinase activ...    »
 
Journal title abbreviation:
Infect Immun 
Year:
2008 
Journal volume:
76 
Journal issue:
Pages contribution:
3992-9 
Language:
eng 
Print-ISSN:
0019-9567 
TUM Institution:
Chirurgiesche Klinik und Poliklinik