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Dokumenttyp:
journal article 
Autor(en):
Keates, AC; Tummala, S; Peek, RM; Csizmadia, E; Kunzli, B; Becker, K; Correa, P; Romero-Gallo, J; Piazuelo, MB; Sheth, S; Kelly, CP; Robson, SC; Keates, S 
Titel:
Helicobacter pylori infection stimulates plasminogen activator inhibitor 1 production by gastric epithelial cells. 
Abstract:
Chronic infection with the gastric pathogen Helicobacter pylori significantly increases the risk of developing atrophic gastritis, peptic ulcer disease, and gastric adenocarcinoma. H. pylori strains that possess the cag pathogenicity island, which translocates CagA into the host cells, augment these risks. The aim of this study was to determine the molecular mechanisms through which H. pylori upregulates the expression of plasminogen activator inhibitor 1 (PAI-1), a member of the urokinase activ...    »
 
Zeitschriftentitel:
Infect Immun 
Jahr:
2008 
Band / Volume:
76 
Heft / Issue:
Seitenangaben Beitrag:
3992-9 
Sprache:
eng 
Print-ISSN:
0019-9567 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik