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Document type:
journal article 
Author(s):
Michalski, CW; Erkan, M; Sauliunaite, D; Giese, T; Stratmann, R; Sartori, C; Giese, NA; Friess, H; Kleeff, J 
Title:
Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer. 
Abstract:
Efficacy of chemotherapy for pancreatic cancer may be improved by tailoring it to individual chemosensitivity profiles. Identification of nonresponders before initiation of treatment may help to avoid side effects. In this study, primary pancreatic cancer cells were isolated from 18 patients undergoing pancreaticoduodenectomy for pancreatic cancer. Eight commonly used pancreatic cancer cell lines were used as controls. Ex vivo chemosensitivity for gemcitabine, 5-fluorouracil, mitomycin-C, cispla...    »
 
Journal title abbreviation:
Br J Cancer 
Year:
2008 
Journal volume:
99 
Journal issue:
Pages contribution:
760-7 
Language:
eng 
Print-ISSN:
0007-0920 
TUM Institution:
Chirurgiesche Klinik und Poliklinik