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Document type:
journal article 
Author(s):
Reiser-Erkan, C; Erkan, M; Pan, Z; Bekasi, S; Giese, NA; Streit, S; Michalski, CW; Friess, H; Kleeff, J 
Title:
Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma. 
Abstract:
BACKGROUND: Pim-1 is a proto-oncogene involved in cell survival, differentiation and proliferation in several hematologic and epithelial malignancies. Clinically, absence of Pim-1 expression correlates with poor prognosis in prostate cancer. In the present study, the expression of Pim-1 is analyzed in pancreatic cancer and correlated to clinicopathological parameters. RESULTS: Compared to benign, inflammatory and pre-malignant conditions (i.e., the normal pancreas, chronic pancreatitis and benig...    »
 
Journal title abbreviation:
Cancer Biol Ther 
Year:
2008 
Journal volume:
Journal issue:
Pages contribution:
1352-9 
Language:
eng 
Print-ISSN:
1538-4047 
TUM Institution:
Chirurgiesche Klinik und Poliklinik