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- Dokumenttyp:
- Article
- Autor(en):
- Höfling, SB; Hultsch, C; Wester, HJ; Heinrich, MR
- Titel:
- Radiochemical F-18-fluoroarylation of unsaturated alpha-, beta- and gamma-amino acids, application to a radiolabelled analogue of baclofen
- Abstract:
- Unsaturated alpha-, beta- and gamma-amino acids have been investigated as substrates for the reductive Meerwein arylation. Radical reactions of this type have been shown to be a valuable tool for the fast and efficient introduction of the 4-[F-18]fluorophenyl group into precursor molecules allowing short-time syntheses of potential PET radiotracers, which would be more difficult to access by other methods. (C) 2008 Elsevier Ltd. All rights reserved.
- Zeitschriftentitel:
- Tetrahedron
- Jahr:
- 2008
- Band / Volume:
- 64
- Heft / Issue:
- 52
- Seitenangaben Beitrag:
- 11846-11851
- Sprache:
- eng
- Print-ISSN:
- 0040-4020
- TUM Einrichtung:
- Klinik und Poliklinik für Nuklearmedizin
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