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Dokumenttyp:
journal article 
Autor(en):
Hamacher, R; Schmid, RM; Saur, D; Schneider, G 
Titel:
Apoptotic pathways in pancreatic ductal adenocarcinoma. 
Abstract:
Pancreatic ductal adenocarcinoma (PDAC) is one of the most common causes of cancer related death. Despite the advances in understanding of the molecular pathogenesis, pancreatic cancer remains a major unsolved health problem. Overall, the 5-year survival rate is less than 5% demonstrating the insufficiency of current therapies. Most cytotoxic therapies induce apoptosis and PDAC cells have evolved a plethora of molecular mechanisms to assure survival. We will present anti-apoptotic strategies wor...    »
 
Zeitschriftentitel:
Mol Cancer 
Jahr:
2008 
Band / Volume:
Seitenangaben Beitrag:
64 
Sprache:
eng 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik