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Document type:
journal article 
Author(s):
Hamacher, R; Schmid, RM; Saur, D; Schneider, G 
Title:
Apoptotic pathways in pancreatic ductal adenocarcinoma. 
Abstract:
Pancreatic ductal adenocarcinoma (PDAC) is one of the most common causes of cancer related death. Despite the advances in understanding of the molecular pathogenesis, pancreatic cancer remains a major unsolved health problem. Overall, the 5-year survival rate is less than 5% demonstrating the insufficiency of current therapies. Most cytotoxic therapies induce apoptosis and PDAC cells have evolved a plethora of molecular mechanisms to assure survival. We will present anti-apoptotic strategies wor...    »
 
Journal title abbreviation:
Mol Cancer 
Year:
2008 
Journal volume:
Pages contribution:
64 
Language:
eng 
TUM Institution:
II. Medizinische Klinik und Poliklinik