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Document type:
journal article 
Author(s):
von Burstin, J; Eser, S; Seidler, B; Meining, A; Bajbouj, M; Mages, J; Lang, R; Kind, AJ; Schnieke, AE; Schmid, RM; Schneider, G; Saur, D 
Title:
Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice. 
Abstract:
Pancreatic cancer is a serious disease with poor patient outcome, often as a consequence of late diagnosis in advanced stages. This is in large part due to the lack of diagnostic tools for early detection. To address this deficiency, we have investigated novel molecular near-infrared fluorescent (NIRF) in vivo imaging techniques in clinically relevant mouse models of pancreatic cancer. Genome wide gene expression profiling was used to identify cathepsin cystein proteases and matrix metalloprotei...    »
 
Journal title abbreviation:
Int J Cancer 
Year:
2008 
Journal volume:
123 
Journal issue:
Pages contribution:
2138-47 
Language:
eng 
Print-ISSN:
0020-7136 
TUM Institution:
II. Medizinische Klinik und Poliklinik; r Medizinische Mikrobiologie, Immunologie und Hygiene