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Document type:
journal article 
Author(s):
Umgelter, A; Reindl, W; Lutz, J; Kreymann, B; Ronco, C; Huber, W; Frank, H; Schmid, RM; Heemann, U 
Title:
Treatment of septic patients with an arginine-based endotoxin adsorber column improves hemodynamics and reduces oxidative stress: results of a feasibility study. 
Abstract:
BACKGROUND: Mortality of severe sepsis and septic shock is unacceptably high. Adsorptive removal of endotoxin may interrupt the inflammatory cascade triggered by lipopolysaccharide. METHODS: Prospective feasibility study with plasma separation and adsorption (PSA) treatment using a novel arginine-coated adsorber column was performed in a tertiary care gastroenterological intensive care unit. RESULTS: 10 patients with severe sepsis/septic shock (median APACHE II score: 27, hospital mortality 40%)...    »
 
Journal title abbreviation:
Blood Purif 
Year:
2008 
Journal volume:
26 
Journal issue:
Pages contribution:
333-9 
Language:
eng 
Print-ISSN:
0253-5068 
TUM Institution:
II. Medizinische Klinik und Poliklinik; r Nephrologie