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Dokumenttyp:
journal article 
Autor(en):
Schneider, G; Hamacher, R; Eser, S; Friess, H; Schmid, RM; Saur, D 
Titel:
Molecular biology of pancreatic cancer--new aspects and targets. 
Abstract:
Pancreatic ductal adenocarcinoma is a dismal disease with a median survival of less than 6 months and an overall 5-year survival rate less than 1%. This bad prognosis is due to early lymphatic and hematogenic dissemination. Effective therapies for locally advanced or metastatic tumors are very limited and curatively resected patients experience relapse in over 80% of cases. Together, these findings reflect the aggressive biology of the disease. Here, we describe molecular mechanisms leading to u...    »
 
Zeitschriftentitel:
Anticancer Res 
Jahr:
2008 
Band / Volume:
28 
Heft / Issue:
3A 
Seitenangaben Beitrag:
1541-50 
Sprache:
eng 
Print-ISSN:
0250-7005 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik; Chirurgiesche Klinik und Poliklinik