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Document type:
journal article 
Author(s):
Schneider, G; Hamacher, R; Eser, S; Friess, H; Schmid, RM; Saur, D 
Title:
Molecular biology of pancreatic cancer--new aspects and targets. 
Abstract:
Pancreatic ductal adenocarcinoma is a dismal disease with a median survival of less than 6 months and an overall 5-year survival rate less than 1%. This bad prognosis is due to early lymphatic and hematogenic dissemination. Effective therapies for locally advanced or metastatic tumors are very limited and curatively resected patients experience relapse in over 80% of cases. Together, these findings reflect the aggressive biology of the disease. Here, we describe molecular mechanisms leading to u...    »
 
Journal title abbreviation:
Anticancer Res 
Year:
2008 
Journal volume:
28 
Journal issue:
3A 
Pages contribution:
1541-50 
Language:
eng 
Print-ISSN:
0250-7005 
TUM Institution:
II. Medizinische Klinik und Poliklinik; Chirurgiesche Klinik und Poliklinik