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Document type:
journal article 
Author(s):
Wagner, M; Koschnick, S; Beilke, S; Frey, M; Adler, G; Schmid, RM 
Title:
Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. 
Abstract:
Epithelial-mesenchymal interactions are essential for growth, differentiation, and regeneration of exocrine and endocrine cells in the pancreas. The keratinocyte growth factor (KGF) is derived from mesenchyme and has been shown to promote epithelial cell differentiation and proliferation in a paracrine fashion. Here, we have examined the effect of ectopic expression of KGF on pancreatic differentiation and proliferation in transgenic mice by using the proximal elastase promoter. KGF transgenic m...    »
 
Journal title abbreviation:
Am J Physiol Gastrointest Liver Physiol 
Year:
2008 
Journal volume:
294 
Journal issue:
Pages contribution:
G1139-47 
Language:
eng 
Print-ISSN:
0193-1857 
TUM Institution:
II. Medizinische Klinik und Poliklinik