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Dokumenttyp:
journal article 
Autor(en):
Wagner, M; Koschnick, S; Beilke, S; Frey, M; Adler, G; Schmid, RM 
Titel:
Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. 
Abstract:
Epithelial-mesenchymal interactions are essential for growth, differentiation, and regeneration of exocrine and endocrine cells in the pancreas. The keratinocyte growth factor (KGF) is derived from mesenchyme and has been shown to promote epithelial cell differentiation and proliferation in a paracrine fashion. Here, we have examined the effect of ectopic expression of KGF on pancreatic differentiation and proliferation in transgenic mice by using the proximal elastase promoter. KGF transgenic m...    »
 
Zeitschriftentitel:
Am J Physiol Gastrointest Liver Physiol 
Jahr:
2008 
Band / Volume:
294 
Heft / Issue:
Seitenangaben Beitrag:
G1139-47 
Sprache:
eng 
Print-ISSN:
0193-1857 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik