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Document type:
journal article 
Author(s):
Stemmler, HJ; Mengele, K; Schmitt, M; Harbeck, N; Laessig, D; Herrmann, KA; Schaffer, P; Heinemann, V 
Title:
Intrathecal trastuzumab (Herceptin) and methotrexate for meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer: a case report. 
Abstract:
Leptomeningeal carcinomatosis represents a rare manifestation of metastatic breast cancer (MBC). We herewith report on a patient suffering from HER2 overexpressing MBC who received intrathecal methotrexate and trastuzumab for meningeal carcinomatosis. A 48-year-old woman was diagnosed with breast cancer in December 2002. Following surgery, six cycles of adjuvant FE100C plus irradiation and, subsequently for 1 year, trastuzumab were given. As a result of disseminated metastatic spread in October...    »
 
Journal title abbreviation:
Anticancer Drugs 
Year:
2008 
Journal volume:
19 
Journal issue:
Pages contribution:
832-6 
Language:
eng 
Print-ISSN:
0959-4973 
TUM Institution:
Frauenklinik und Poliklinik