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Dokumenttyp:
journal article 
Autor(en):
Zischka, H; Larochette, N; Hoffmann, F; Hamöller, D; Jägemann, N; Lichtmannegger, J; Jennen, L; Müller-Höcker, J; Roggel, F; Göttlicher, M; Vollmar, AM; Kroemer, G 
Titel:
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition. 
Abstract:
A pathological increase of the permeability of the mitochondrial membranes may culminate in the irreversible rupture of the mitochondrial outer membrane. Such a permeability transition is lethal because it results in the release of death-inducing molecules from mitochondria and/or metabolic failure. Current methods to assess this outer membrane damage are mostly indirect or scarcely representative of the overall mitochondrial population. Here we present an analytical and preparative approach usi...    »
 
Zeitschriftentitel:
Anal Chem 
Jahr:
2008 
Band / Volume:
80 
Heft / Issue:
13 
Seitenangaben Beitrag:
5051-8 
Sprache:
eng 
Print-ISSN:
0003-2700 
TUM Einrichtung:
r Toxikologie und Umwelthygiene