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Document type:
journal article 
Author(s):
Zischka, H; Larochette, N; Hoffmann, F; Hamöller, D; Jägemann, N; Lichtmannegger, J; Jennen, L; Müller-Höcker, J; Roggel, F; Göttlicher, M; Vollmar, AM; Kroemer, G 
Title:
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition. 
Abstract:
A pathological increase of the permeability of the mitochondrial membranes may culminate in the irreversible rupture of the mitochondrial outer membrane. Such a permeability transition is lethal because it results in the release of death-inducing molecules from mitochondria and/or metabolic failure. Current methods to assess this outer membrane damage are mostly indirect or scarcely representative of the overall mitochondrial population. Here we present an analytical and preparative approach usi...    »
 
Journal title abbreviation:
Anal Chem 
Year:
2008 
Journal volume:
80 
Journal issue:
13 
Pages contribution:
5051-8 
Language:
eng 
Print-ISSN:
0003-2700 
TUM Institution:
Institut für Toxikologie und Umwelthygiene