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Document type:
journal article 
Author(s):
Stangl, S; Gross, C; Pockley, AG; Asea, AA; Multhoff, G 
Title:
Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells. 
Abstract:
This study compared the effects of the human 70-kDa stress protein (Hsp70) peptide, TKDNNLLGRFELSG (TKD), proinflammatory cytokines, or a combination of both on the repertoire of receptors expressed by human natural killer (NK) cells and their capacity to kill human CX colon carcinoma cells, K562 erythroleukemic cells, and leukemic blasts from two patients with acute myelogenous leukemia. Low-dose interleukin (IL) 2/IL-15 and TKD increase the expression density of activatory (NKG2D, NKp30, NKp44...    »
 
Journal title abbreviation:
Cell Stress Chaperones 
Year:
2008 
Journal volume:
13 
Journal issue:
Pages contribution:
221-30 
Language:
eng 
Print-ISSN:
1355-8145 
TUM Institution:
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie