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Dokumenttyp:
journal article 
Autor(en):
Peschel, C; Hartmann, JT; Schmittel, A; Bokemeyer, C; Schneller, F; Keilholz, U; Buchheidt, D; Millan, S; Izquierdo, MA; Hofheinz, RD 
Titel:
Phase II study of plitidepsin in pretreated patients with locally advanced or metastatic non-small cell lung cancer. 
Abstract:
OBJECTIVE: To evaluate the progression-free rate (PFR) at 3 months (13+/-1 weeks), antitumor response, time-to-event efficacy endpoints, and toxicity profile of plitidepsin administered as a 3-h continuous i.v. infusion at a dose of 5mg/m(2), every 2 weeks, to patients with chemotherapy pretreated advanced non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: This was a multicenter, non-randomized, exploratory, phase II study. Treatment lasted until disease progression, unacceptable toxicity...    »
 
Zeitschriftentitel:
Lung Cancer 
Jahr:
2008 
Band / Volume:
60 
Heft / Issue:
Seitenangaben Beitrag:
374-80 
Sprache:
eng 
Print-ISSN:
0169-5002 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik