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Document type:
journal article 
Author(s):
Frank, B; Rigas, SH; Bermejo, JL; Wiestler, M; Wagner, K; Hemminki, K; Reed, MW; Sutter, C; Wappenschmidt, B; Balasubramanian, SP; Meindl, A; Kiechle, M; Bugert, P; Schmutzler, RK; Bartram, CR; Justenhoven, C; Ko, YD; Brüning, T; Brauch, H; Hamann, U; Pharoah, PP; Dunning, AM; Pooley, KA; Easton, DF; Cox, A; Burwinkel, B 
Title:
The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study. 
Abstract:
A recent study on an Asian population reported a six-nucleotide insertion-deletion polymorphism (-652 6N del) in the CASP8 promoter region to be strongly associated with a decreased risk of multiple types of cancer, including breast cancer (BC). Here, we investigate the effect of this deletion in four independent large European BC case-control studies, including data from a total of 7,753 cases and 7,921 controls. The combined per allele odds ratio (OR) was 0.97 (95% confidence interval (CI), 95...    »
 
Journal title abbreviation:
Breast Cancer Res Treat 
Year:
2008 
Journal volume:
111 
Journal issue:
Pages contribution:
139-44 
Language:
eng 
Print-ISSN:
0167-6806 
TUM Institution:
Frauenklinik und Poliklinik