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Dokumenttyp:
journal article 
Autor(en):
Flockerzi, A; Ruggieri, A; Frank, O; Sauter, M; Maldener, E; Kopper, B; Wullich, B; Seifarth, W; Müller-Lantzsch, N; Leib-Mösch, C; Meese, E; Mayer, J 
Titel:
Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project. 
Abstract:
BACKGROUND: A significant proportion of the human genome is comprised of human endogenous retroviruses (HERVs). HERV transcripts are found in every human tissue. Expression of proviruses of the HERV-K(HML-2) family has been associated with development of human tumors, in particular germ cell tumors (GCT). Very little is known about transcriptional activity of individual HML-2 loci in human tissues, though. RESULTS: By employing private nucleotide differences between loci, we assigned approximate...    »
 
Zeitschriftentitel:
BMC Genomics 
Jahr:
2008 
Band / Volume:
Seitenangaben Beitrag:
354 
Sprache:
eng 
TUM Einrichtung:
r Virologie