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Dokumenttyp:
journal article 
Autor(en):
Lukowski, R; Weinmeister, P; Bernhard, D; Feil, S; Gotthardt, M; Herz, J; Massberg, S; Zernecke, A; Weber, C; Hofmann, F; Feil, R 
Titel:
Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis. 
Abstract:
BACKGROUND: Nitric oxide (NO) is of crucial importance for smooth muscle cell (SMC) function and exerts numerous, and sometimes opposing, effects on vascular restenosis. Although cGMP-dependent protein kinase type I (cGKI) is a principal effector of NO, the molecular pathway of vascular NO signaling in restenosis is unclear. The purpose of this study was to examine the functional role of the smooth muscle cGMP/cGKI signaling cascade in restenosis of vessels. METHODS AND RESULTS: Tissue-specific...    »
 
Zeitschriftentitel:
Arterioscler Thromb Vasc Biol 
Jahr:
2008 
Band / Volume:
28 
Heft / Issue:
Seitenangaben Beitrag:
1244-50 
Sprache:
eng 
Print-ISSN:
1079-5642 
TUM Einrichtung:
r Pharmakologie und Toxikologie; I. Medizinische Klinik und Poliklinik