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Dokumenttyp:
journal article 
Autor(en):
Nischwitz, V; Berthele, A; Michalke, B 
Titel:
Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: An approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier. 
Abstract:
Neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are gaining increasing relevance in our aging society. However, the complex multifactorial mechanisms of these diseases are not sufficiently understood yet. Several studies indicate that metal ions play an important role in the promotion of these diseases. Consequently, the transport pathways of metals and their species to the brain are of special interest. Following oral or inhalative uptake metals are absorbed and dist...    »
 
Zeitschriftentitel:
Anal Chim Acta 
Jahr:
2008 
Band / Volume:
627 
Heft / Issue:
Seitenangaben Beitrag:
258-69 
Sprache:
eng 
Print-ISSN:
0003-2670 
TUM Einrichtung:
Neurologische Klinik und Poliklinik