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Document type:
journal article 
Author(s):
Nischwitz, V; Berthele, A; Michalke, B 
Title:
Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: An approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier. 
Abstract:
Neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are gaining increasing relevance in our aging society. However, the complex multifactorial mechanisms of these diseases are not sufficiently understood yet. Several studies indicate that metal ions play an important role in the promotion of these diseases. Consequently, the transport pathways of metals and their species to the brain are of special interest. Following oral or inhalative uptake metals are absorbed and dist...    »
 
Journal title abbreviation:
Anal Chim Acta 
Year:
2008 
Journal volume:
627 
Journal issue:
Pages contribution:
258-69 
Language:
eng 
Print-ISSN:
0003-2670 
TUM Institution:
Neurologische Klinik und Poliklinik