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Dokumenttyp:
journal article 
Autor(en):
Dardalhon, V; Korn, T; Kuchroo, VK; Anderson, AC 
Titel:
Role of Th1 and Th17 cells in organ-specific autoimmunity. 
Abstract:
CD4(+) IFN-gamma-producing Th1 cells have long been associated with the pathogenesis of many organ-specific autoimmune diseases; however, the observation of disease in mice deficient in molecules involved in Th1 cell differentiation raised the possibility that other effector T cells were responsible for inducing autoimmunity. Recently, a new CD4(+) effector T cell subset that produces IL-17 (Th17) has emerged. The fact that Th17 cells are highly auto-pathogenic has fueled a debate as to what ro...    »
 
Zeitschriftentitel:
J Autoimmun 
Jahr:
2008 
Band / Volume:
31 
Heft / Issue:
Seitenangaben Beitrag:
252-6 
Sprache:
eng 
Print-ISSN:
0896-8411 
TUM Einrichtung:
Neurologische Klinik und Poliklinik