User: Guest  Login
Document type:
journal article 
Author(s):
Buttmann, M; Nowak, E; Kroner, A; Hemmer, B; Lesch, KP; Rieckmann, P 
Title:
Analysis of the Stathmin rs182455 Single Nucleotide Promoter Polymorphism in Patients with Multiple Sclerosis 
Abstract:
Stathmin, a steroid-responsive regulatory protein of oligodendrocyte migration and survival, is highly expressed in active brain lesions of patients with multiple sclerosis (MS) and probably involved in myelin degeneration and repair. Here, we analyzed a single nucleotide polymorphism (rs182455) within the stathmin promoter that is close to a putative steroid-responsive element and has a high minor allelic frequency, in 647 clinically well characterized MS patients and 519 healthy controls. Alle...    »
 
Journal title abbreviation:
J Neurogenet 
Year:
2008 
Journal volume:
22 
Journal issue:
Pages contribution:
181-186 
Language:
eng 
Print-ISSN:
0167-7063 
TUM Institution:
Neurologische Klinik und Poliklinik