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Dokumenttyp:
journal article 
Autor(en):
Borel, P; Benkhoucha, M; Weber, MS; Zamvil, SS; Santiago-Raber, ML; Lalive, PH 
Titel:
Glatiramer acetate treatment does not modify the clinical course of (NZB x BXSB)F1 lupus murine model. 
Abstract:
Glatiramer acetate (GA, copolymer-1, Copaxone), a therapy approved for treatment of multiple sclerosis (MS), prevents and reverses experimental autoimmune encephalomyelitis, the animal model of MS. In central nervous system autoimmune disease, GA is thought to act through modulation of antigen-presenting cells, such as monocytes, mediating an antigen-independent T(h)2 shift and development of FoxP3+ regulatory T cells. Recent reports indicate that GA may also be effective in models of other auto...    »
 
Zeitschriftentitel:
Int Immunol 
Jahr:
2008 
Band / Volume:
20 
Heft / Issue:
10 
Seitenangaben Beitrag:
1313-9 
Sprache:
eng 
Print-ISSN:
0953-8178 
TUM Einrichtung:
Neurologische Klinik und Poliklinik