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Dokumenttyp:
journal article 
Autor(en):
Weidinger, S; O'Sullivan, M; Illig, T; Baurecht, H; Depner, M; Rodriguez, E; Ruether, A; Klopp, N; Vogelberg, C; Weiland, SK; McLean, WH; von Mutius, E; Irvine, AD; Kabesch, M 
Titel:
Filaggrin mutations, atopic eczema, hay fever, and asthma in children. 
Abstract:
BACKGROUND: Mutations in the filaggrin gene (FLG) have been shown to play a significant role in ichthyosis vulgaris and eczema, 2 common chronic skin diseases. However, their role in the development of other atopic diseases such as asthma and rhinitis has not yet been clarified in large population-based studies. OBJECTIVES: To study the effect of FLG mutations at the population level and their effect on other atopic phenotypes. METHODS: Association analysis of the 2 common FLG-null mutations R50...    »
 
Zeitschriftentitel:
J Allergy Clin Immunol 
Jahr:
2008 
Band / Volume:
121 
Heft / Issue:
Seitenangaben Beitrag:
1203-1209.e1 
Sprache:
eng 
Print-ISSN:
0091-6749 
TUM Einrichtung:
r Dermatologie und Allergologie; r Medizinische Statistik und Epidemiologie