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Document type:
journal article 
Author(s):
Graf, N; Herrmann, K; den Hollander, J; Fend, F; Schuster, T; Wester, HJ; Senekowitsch-Schmidtke, R; Büschenfelde, CM; Peschel, C; Schwaiger, M; Dechow, T; Buck, AK 
Title:
Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment. 
Abstract:
PURPOSE: Positron emission tomography with the thymidine analogue 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) has been reported to closely reflect lymphoma proliferation in vivo. In this preclinical study, we have investigated if FLT can also be utilized for imaging therapy-induced alterations of the nucleoside metabolism and if FLT is a surrogate marker for early response to cytotoxic treatment. MATERIALS AND METHODS: Immunodeficient mice bearing high-grade lymphoma xenotransplants were treated wi...    »
 
Journal title abbreviation:
Mol Imaging Biol 
Year:
2008 
Journal volume:
10 
Journal issue:
Pages contribution:
349-55 
Language:
eng 
Print-ISSN:
1536-1632 
TUM Institution:
III. Medizinische Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik; r Medizinische Statistik und Epidemiologie