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Dokumenttyp:
journal article 
Autor(en):
Calatzis, A; Peetz, D; Haas, S; Spannagl, M; Rudin, K; Wilmer, M 
Titel:
Prothrombinase-induced clotting time assay for determination of the anticoagulant effects of unfractionated and low-molecular-weight heparins, fondaparinux, and thrombin inhibitors. 
Abstract:
The prothrombinase-induced clotting time assay (PiCT, Pentapharm, Basel, Switzerland) is a clotting assay sensitive to factor Xa and factor IIa inhibitors. It is based on the addition of factor Xa and snake venom RVV-V (Russell viper venom factor V activator) specifically activating factor V and phospholipids to platelet-poor plasma. Following an incubation time, the mixture is recalcified and the clotting time is determined. An almost linear dose-response and high sensitivity of the assay for u...    »
 
Zeitschriftentitel:
Am J Clin Pathol 
Jahr:
2008 
Band / Volume:
130 
Heft / Issue:
Seitenangaben Beitrag:
446-54 
Sprache:
eng 
Print-ISSN:
0002-9173 
TUM Einrichtung:
r experimentelle Onkologie und Therapieforschung